1.Development of thulium-doped fiber laser urinary system lithotripsy instrument

Urinary tract stones are one of the most common diseases, and they are also the most complex and difficult to treat among urological diseases. In recent years, the incidence of urinary system stones has gradually increased, and it is getting younger. The prevention and treatment of stones has a long way to go. Compared with traditional extracorporeal shock wave lithotripsy and pneumatic ballistic lithotripsy, holmium laser lithotripsy has the advantages of fast wound healing, good hemostasis effect, no bleeding during surgery, clear vision, laser can be transmitted with optical fiber, and can achieve minimally invasive or non-invasive surgery, and is safe. Higher advantage. However, the currently commonly used holmium laser lithotripsy has low efficiency and high laser maintenance costs. Compared with the holmium laser with a wavelength of 2120nm, the thulium-doped fiber laser with a wavelength of 1908nm or 1940nm is closer to the absorption peak of water, has a large tunable range of repetition frequency and high beam quality. In recent years, foreign studies have found that it can Improving the efficiency of lithotripsy is expected to become the next generation of laser light source for clinical lithotripsy. The development of laser light source technology in this band in China lags behind, and commercial products are single. There is a gap in research on this type of laser lithotripsy. Therefore, thulium-doped fiber laser lithotripsy technology has begun to become a hot spot in international research and application. This technology is based on a self-developed high-power thulium-doped fiber laser and a therapeutic instrument that can be used for urinary system lithotripsy, providing a new technological approach for efficient, maintenance-free laser lithotripsy.

Thulium-doped fiber laser urinary system treatment instrument

2. Development of laser welding equipment for transparent polymer materials

With the development and demand of microelectromechanical system technology ( Micro Electro-Mechanical System-MEMS ), polymers, as a kind of polymer material, have a wide range of types, superior mechanical properties, excellent biological and chemical compatibility and low cost. , allowing polymer materials to replace certain silicon, quartz glass, etc., and be used in MEMS devices as base materials, functional materials or sensitive element materials. Therefore, polymers are widely used in biological microfluidic chips, optical devices, microfluidic sensors, information storage and other polymers (polymethylmethacrylate PMMA , polyethylene terephthalate PET , cyclic olefin copolymer COC , etc.) The field of micro devices has huge development potential.

However, polymer microdevices are difficult to injection mold in one go, and their molding requires a combination of photolithography, imprinting, welding and other technologies. Compared with traditional ultrasonic welding and vibration friction welding, laser welding has many advantages: non-contact, clean and hygienic, particle-free, precise focusing, enabling precision micro-nano processing, good welding quality, and high efficiency. Therefore, laser welding polymer material technology is called "A Neat Thing". Due to the light absorption properties of the materials, transparent and white polymers are the two most difficult materials to weld, and many microdevices currently use transparent polymer materials. Therefore, the development of efficient and convenient transparent polymer laser micro-nano welding technology is crucial to improving the performance of polymer-based microdevices and promoting the development of polymer-based microdevices. It has become a hot research issue in the field of polymer welding in recent years. Especially laser transmission welding (Laser Transmission Welding , LTW).

Based on our self-developed thulium-doped fiber laser in the mid-infrared band, we have developed equipment suitable for laser welding of transparent, translucent and white plastics. And realized the welding of micro gearboxes, microfluidic chips, medical beauty and other products.

Transparent plastic laser welding machine based on galvanometer scanning

Physical picture of welding sample

3.Future research plans and expected results

Develop and optimize thulium-doped fiber laser to achieve high peak power quasi-continuous thulium-doped fiber laser output and finalize the thulium-doped fiber laser lithotripsy.

Realize micro-nano welding of transparent polymer materials.

Realize laser welding of polymer material microfluidic chips.