1. Education And Work Experience

Ø Education Experience

l 2018-2024, Columbia University, Mechanical Engineering, Doctor of Philosophy

l 2016-2018, University of Electronic Science and Technology of China, Material Engineering, Master of Engineering

l 2012-2016, University of Electronic Science and Technology of China, Biotechnology, Bachelor of Science

Ø Work Experience

l 2024-Present, Shenzhen Technology University, Sino-German College of Intelligent Manufacturing，Assistant Professor

2. Research Field and Achievements

Ø Project Experience

[1] “Validating Rapid Microfluidic Isolation of Personalized Aptamers for Monitoring Minimal Residual Disease in Multiple Myeloma”, Key member, National Institutes of Health, 2018/08-2021/07, $1,170,684;

[2] “A Practical Approach to Tumor-Specific Aptamers for B-Cell Hematologic Malignancies”, Key member, National Institutes of Health, 2022/05-2025/04, $600,000;

[3] “Towards rapid measurement of antibiotics in critical care setting”, Key member, National Institutes of Health, 2022/09-2026/05, $2,030,312.

Ø Selected Publications

[1] Kechun Wen, Wenting Dai, Xin Meng, Qiao Lin*, Jia Wei, Liang Tong, Steven K Taylor, Sergei A Rudchenko, Milan N Stojanovic*, Gary Kalantarov, Ilya Trakht*. “Rapid isolation of anti-idiotype aptamers for quantification of human monoclonal antibodies against SARS-CoV-2 spike protein”. Biosensors and Bioelectronics 246 (2024): 115842. (JCR1, IF: 10.7)

[2] Kechun Wen, Xin Meng, Chengxi Wang, Jingyang Zhao, Samantha Botros, Qiao Lin*. “Assessing aptamer-analyte binding kinetics by microfluidic fluorescence microscopy”. Sensors and Actuators B: Chemical 401 (2024): 135018. (JCR1, IF: 8.0)

[3] Kechun Wen, Xin Meng, Kathie Lara, Qiao Lin*. “Cost-effective evaluation of Aptamer candidates in SELEX-based Aptamer isolation." Talanta 275 (2024): 126103. (JCR1, IF: 5.6)

[4] Kechun Wen, Yannan Chen, Xin Meng, Samantha Botros, Wenting Dai, Milan N Stojanovic*, Raju Tomer*, Qiao Lin*. "A microfluidic dual-aptamer sandwich assay for rapid and cost-effective detection of recombinant proteins." Microchemical Journal 188 (2023): 108454. (JCR1, IF: 4.9)

[5] Xin Meng^#, Kechun Wen^# (equal contribution), Marimuthu Citartan, Qiao Lin*. "A comparative study of aptamer isolation by conventional and microfluidic strategies." Analyst 148.4 (2023): 787-798. (JCR2, IF: 3.6)

[6] Liwei Dong^#, Yuanpeng Liu^#, Kechun Wen^# (equal contribution), Dongjiang Chen, Dewei Rao, Jipeng Liu, Botao Yuan, Yunfa Dong, Ze Wu, Yifang Liang, Mengqiu Yang, Jianyi Ma, Chunhui Yang, Chuan Xia, Baoyu Xia, Jiecai Han, Gongming Wang*, Zaiping Guo*, Weidong He*. “High‐polarity fluoroalkyl ether electrolyte enables solvation‐free Li+ transfer for high‐rate lithium metal batteries." Advanced Science 9.5 (2022): 2104699. (JCR 1, IF: 15.1)

[7] Wenting Dai, Kechun Wen, Xin Meng, Shifeng Yu, Jingyang Zhao, Qiao Lin*. "Aptameric Metal–Organic Framework Nanobiosensor." ACS Applied Nano Materials 2024, Vol. 7(14): 17081-17091.(JCR 2, IF: 5.3)

[8] Timothy R Olsen, Claudia Tapia-Alveal, Kechun Wen, Tilla S Worgall, Milan N Stojanovic*, Qiao Lin*. "Microfluidic isolation of aptamers with affinity towards multiple myeloma monoclonal immunoglobulins." Biomedical Microdevices 25.1 (2023): 3. (JCR 3, IF: 3)

[9] Cheng Bai, Xin Meng, Kechun Wen, Marimuthu Citartan, Chaohui Wang, Shifeng Yu, Qiao Lin*. "Surface acoustic wave-assisted microfluidic isolation of aptamers." Microfluidics and Nanofluidics 26.6 (2022): 43. (JCR 2, IF: 2.3)

[10] Botao Yuan, Kechun Wen, Dongjiang Chen, Yuanpeng Liu, Yunfa Dong, Chao Feng, Yupei Han, Jiecai Han, Yongqi Zhang, Chuan Xia, Andy Sun, Weidong He*. "Composite separators for robust high rate lithium ion batteries." Advanced Functional Materials 31.32 (2021): 2101420. (JCR 1, IF: 18.5)

[11] Kechun Wen, Mingfu Xia, Pan Deng, Weiqiang Lv, Weidong He*. "A sandwich-structured double-battery device for direct evaluation of lithium diffusion coefficients and phase transition in electrodes of lithium ion batteries." Chemical Engineering Science 200 (2019): 80-86. (JCR 1, IF: 3.87)

[12] Kechun Wen, Chao Tan, and Weidong He*. "Synergistic effects of thermal expansion-induced variation in the electrode microstructure on polarization loss in solid oxide fuel cells." Journal of Materials Chemistry A 5.6 (2017): 2768-2773. (JCR 1, IF: 10.7)

[13] Kechun Wen, Yupei Han, Minda Zou, Weiqiang Lv, Weidong He*. "Interfacial strain effect on gas transport in nanostructured electrodes of solid oxide fuel cells." Journal of Power Sources 291 (2015): 126-131. (JCR 1, IF: 8.1)

[14] Kechun Wen, and Weidong He*. "Can oriented-attachment be an efficient growth mechanism for the synthesis of 1D nanocrystals via atomic layer deposition?." Nanotechnology 26.38 (2015): 382001. (JCR 2, IF: 2.9)

[15] Kechun Wen, Kelvin HL Zhang, Wei Wang, Junhao Lin, Weiqiang Lv, Bin Wang, Zhiming M Wang, James H Dickerson, Xin Guo, Weidong He*. "Physical justification for ionic conductivity enhancement at strained coherent interfaces." Journal of Power Sources 285 (2015): 37-42. (JCR 1, IF: 8.1)

[16] Kechun Wen, Weiqiang Lv, and Weidong He*. "Interfacial lattice-strain effects on improving the overall performance of micro-solid oxide fuel cells." Journal of Materials Chemistry A 3.40 (2015): 20031-20050. (JCR 1, IF: 10.7)

3. Teaching Summary

l Signals and Systems;

l Microelectromechanical Systems (MEMS);