Urinary tract stones are one of the most common diseases, and they are also the most complex and difficult to treat among urological diseases. In recent years, the incidence of urinary system stones has gradually increased, and it is getting younger. The prevention and treatment of stones has a long way to go. Compared with traditional extracorporeal shock wave lithotripsy and pneumatic ballistic lithotripsy, holmium laser lithotripsy has the advantages of fast wound healing, good hemostasis effect, no bleeding during surgery, clear vision, laser can be transmitted with optical fiber, and can achieve minimally invasive or non-invasive surgery, and is safe. Higher advantage. However, the currently commonly used holmium laser lithotripsy has low efficiency and high laser maintenance costs. Compared with the holmium laser with a wavelength of 2120nm, the thulium-doped fiber laser with a wavelength of 1908nm or 1940nm is closer to the absorption peak of water, has a large tunable range of repetition frequency and high beam quality. In recent years, foreign studies have found that it can Improving the efficiency of lithotripsy is expected to become the next generation of laser light source for clinical lithotripsy. The development of laser light source technology in this band in China lags behind, and commercial products are single. There is a gap in research on this type of laser lithotripsy. Therefore, thulium-doped fiber laser lithotripsy technology has begun to become a hot spot in international research and application. This technology is based on a self-developed high-power thulium-doped fiber laser and a therapeutic instrument that can be used for urinary system lithotripsy, providing a new technological approach for efficient, maintenance-free laser lithotripsy.

1) Preliminary research basis and results 

    Physical prototype picture:

2) Research plan and expected results 

Develop and optimize thulium-doped fiber laser, achieve high peak power quasi-continuous thulium-doped fiber laser output, and realize the development of thulium-doped fiber laser lithotripsy. 

Realize micro-nano welding of transparent polymer materials. 

Realize laser welding of polymer material microfluidic chips.